A UPS cargo plane crashed and exploded in a massive fireball Tuesday while taking off from the company’s global aviation hub in Louisville, Kentucky, killing at least four people and injuring 11, authorities said.
The plane crashed about 5:15 p.m. as it was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport.
BREAKING: 🔴
— Open Source Intel (@Osint613) November 4, 2025
Here is aerial footage of the UPS cargo plane crash near Louisville, Kentucky airport. Several buildings are on fire, reports of multiple victims. pic.twitter.com/rgTfH1P0Rh
Breaking News. Spirit-Filled Stories. Subscribe to Charisma on YouTube now!
Video showed flames on the plane’s left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball. The video also revealed portions of a building’s shredded roof next to the end of the runway.
At least four people were killed, said Officer Jonathan Biven, an airport spokesperson.
Among the 11 who were hurt, some had “very significant” injuries, Kentucky Gov. Andy Beshear said.
“Anybody who has seen the images, the video, knows how violent this crash is,” he said.
Beshear said he didn’t know the status of the three crew members aboard the plane, a McDonnell Douglas MD-11 made in 1991.
UPS’s largest package handling facility is in Louisville. The hub employs thousands of workers, has 300 daily flights and sorts more than 400,000 packages an hour.
“We all know somebody who works at UPS,” Louisville Metro Council member Betsy Ruhe said. “And they’re all texting their friends, their family, trying to make sure everyone is safe. Sadly, some of those texts are probably going to go unanswered. My heart goes out to those families and those friends.”
UPS acknowledged the crash in a brief statement and said the National Transportation Safety Board would handle the investigation.
The airport, meanwhile, was shut down and wasn’t expected to resume operations until Wednesday morning.
“We don’t know how long it’s going to take to render that scene safe,” said Louisville Police Chief Paul Humphrey.
Join Charisma Magazine Online to follow everything the Holy Spirit is doing around the world!
The governor said a business, Kentucky Petroleum Recycling, appeared to be “hit pretty directly,” and a nearby auto parts operation was also affected.
To read the full story, visit our content partners at CBN News.
Reprinted with permission from cbn.com. Copyright © 2025 The Christian Broadcasting Network Inc. All rights reserved.











