Fri. Dec 5th, 2025

The #1 Anti-Depressant: God’s Word

depressed woman

Make a choice to rejoice. As you “eat” the Word, God will replace your depression and despair with peace and joy. Make Psalm 103:2 your daily confession: “I will bless the Lord and not forget the glorious things He does for me” (The Living Bible).

A FINAL PRESCRIPTION Have you ever noticed that depression and anxiety often come at night? God in His mercy has given us a nighttime prescription in Psalm 4:4,7-8: “Meditate within your heart on your bed, and be still….I will both lie down in peace, and sleep; for You alone, O Lord, make me dwell in safety” (NKJV). You can go to bed and have sweet dreams; you can lay your head down and not be depressed.

What about when you wake up? Have you ever faced discouragement in the morning? God has written a prescription for that too! Psalm 5 is your morning dose of the Word: “Give heed to the voice of my cry, my King and my God, for to You I will pray. My voice You shall hear in the morning, O Lord; in the morning I will direct it to You, and I will look up” (Ps. 5:2-3).

Morning, noon and night, you can take your supernatural antidepressant. As you focus on God’s Word, listen to the Spirit’s voice and allow Jesus to give you a double portion of joy, you can walk in victory over every spirit of depression that tries to disable you or sidetrack your life! God’s prescription for joy will keep you depression-free!


Marilyn Hickey is founder and president of Marilyn Hickey Ministries in Denver. She is an anointed teacher and author whose ministry reaches the world through television, books and crusades.

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